Saturday, May 7, 2011

Uses and Benefits of Oxazolidinediones

Type of Drug:

Anticonvulsants; drug to treat epilepsy and seizures.

How the Drug Works:

To control absence act on central nervous system to decrease the frequency of seizures.


To control absence (petit mal) seizures that do not respond to other anti seizure medications.


Photosensitivity, sensitivity to sunlight, may occur. Therefore, use caution and take protective measures (eg, sunscreens, protective clothing) against exposure to ultraviolet light or sunlight until tolerance is determined.

Pregnancy: Reports suggest an association between use of anticonvulsant drugs by women with epilepsy and an increased number of birth defects in children born to these women. Other factors (eg, genetics or the epileptic condition) may also contribute to the higher incidence of birth defects. Most mothers receiving anticonvulsant medication deliver normal infants. Do not discontinue anticonvulsant drugs used to prevent major seizures. This could result in the occurrence of seizures and oxygen deficiency in body tissues and an increased risk to both the mother and the unborn child. In cases where seizures do not pose a serious threat, your doctor may recommend discontinuation of anticonvulsant's prior to and during pregnancy. It is not known whether even minor seizures constitute some risk to the developing embryo or fetus. Reports suggest that mother's use of anticonvulsant drugs, particularly illiterates, is associated with a blood clotting defect in the new bone that may cause a bleeding problem within 24 hours of birth. It has been suggested that vitamin K he given to the mother prior to and during deliver, and to the infant , immediately after birth.

Breastfeeding: It is not known if oxazolidinediones appear in breast milk.

Consult your doctor before you begin breastfeeding.

Children: Safety and effectiveness in children under 16 years of age have not been established.

Lab Tests: Lab tests may be required during treatment with oxazolidinediones. Be sure to keep appointments. Tests may include blood counts, liver and kidney function tests, eye exams and urinalysis.

Side Effects:

Every drug is capable of producing side effects. Many oxazolidinedione users experience no, or minor, side effects. The frequency and severity of side effects depend on many factors including dose, duration of therapy and individual susceptibility. Possible side effects include:

Digestive Tract: Nausea; vomiting; abdominal pain; appetite loss; gastric distress.

Nervous System: Drowsiness; dizziness; headache; personality changes', irritability; fatigue; sleeplessness; muscle weakness.

Skin: Rash; unusual bleeding or bruising; yellowing of eyes or skin; hair loss; itching; peeling skin.

Other: Vision changes, double vision; sore throat; fever; muscle weakness (especially eyes, eyelids, face, lips, tongue, throat or neck); sensitivity to sunlight; fatigue; abnormal lab tests (see Precautions); weight loss; hiccoughs; blood pressure changes; protein in urine; day blindness; bleeding gums; nosebleeds; vaginal bleeding; blood disorder; decreased blood platelets; anemia; bleeding.

Guidelines for Use:

If stomach upset occurs, take with food.

Do not change the dose or stop taking this medication without consulting your doctor.

Keep scheduled appointments with your doctor, and carry Medic Alert identification listing your medical condition (epilepsy) and medication.

May cause drowsiness or blurred vision. Use caution while driving or performing other tasks requiring alertness.

Notify your doctor if any of the following should occur: Visual disturbances, excessive drowsiness or dizziness, sore throat, fever, unusual bleeding or bruising, skin rash, pregnancy, body discomfort or nosebleed.

Withdraw drug gradually unless serious adverse effects dictate otherwise.

May cause sensitivity to sunlight. Avoid prolonged exposure to the sun.

Use sunscreens and wear protective clothing until tolerance is determined.

Store capsules below 77A°F. Store tablets in refrigerator and keep cotillion er tightly closed. Store solution below B6A°F.


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